Influence of 5α-dihydrotestosterone and 17β-estradiol on human Sertoli cells metabolism
نویسندگان
چکیده
منابع مشابه
Effects of 5α-Dihydrotestosterone and 17β-Estradiol on the Mouse Ovarian Follicle Development and Oocyte Maturation
We have previously reported that androstenedione induces abnormalities of follicle development and oocyte maturation in the mouse ovary. In granulosa cells of the ovarian follicle, androstenedione is aromatized to 17β-estradiol (E2). To determine whether the androgen or estrogen acts directly on the follicle to induce the above-mentioned abnormalities, we compared the effects of a non-aromatiza...
متن کاملComparison of the effects of 17β- estradiol treated and untreated mesenchymal stem cells on ameliorating animal model of multiple sclerosis
Objective(s): The current investigation was undertaken to evaluate the effects of 17β- estradiol (17β-ED) on the potential of the mesenchymal stem cells (MSCs) for modulation of immunity responses in an animal model of multiple sclerosis (MS).Materials and Methods: After isolation of MSCs, cells were cultured in presence of 100 nM 17β-ED for 24 hr. Modeling of experimental autoimmune encephalom...
متن کاملSpecific binding of estradiol and dihydrotestosterone in human mammary cancers.
Estrogen and dihydrotestosterone receptors were detected by agar gel electrophoresis in 224 human mammary tumor biopsies. Approximately half of the tumor specimens revealed measurable amounts of estradiol receptors, whereas only 20% contained dihydrotestosterone receptors. The average concentration of spare estrogetmenopausal than in the premenopausal group, but this was not found to be the cas...
متن کاملSpecific Binding of Estradiol and Dihydrotestosterone in Human Mammary Cancers1
chased from New England Nuclear, Boston, Mass. The pun ity (>94.0%) was checked by thin-layer chromatography. The antiestrogenic compound U. 11,100 (Nafoxidine) was a gift from the Upjohn Company, Kalamazoo, Mich. Cypro terone acetate was provided by Schening AG, Berlin, Gen many. Agar purum, human serum albumin, and rabbit anti serum against human serum albumin were obtained from Behningwerke,...
متن کاملN-tert-Butyl-5α-androstane-17β-carboxamide
The title compound, C(24)H(41)NO, is a new derivative of the anti-HIV steroid 17β-(N-tert-butyl-amino-carbon-yl)androst-4-en-3-one. There are four rings in the structure and these are trans-fused. The three six-membered rings exhibit chair conformations, while the five-membered ring adopts an envelope conformation.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Andrology
سال: 2011
ISSN: 0105-6263
DOI: 10.1111/j.1365-2605.2011.01205.x